How it's believed to work


Download the Parent and Caregiver Brochure:

Acthar Gel is a prescription medication containing naturally sourced adrenocorticotropic [ah-dree-noh-kor-tih-coh-trohp-ik] hormone (ACTH). It's a medication that works with your child's body to help it produce its own natural steroids.

While the exact way that Acthar Gel works in the body is unknown, further studies are being conducted. This information is based on laboratory data, and how it relates to patient benefits is unknown.

When your doctor prescribes Acthar Gel, you and your child may begin what is typically a 4-week treatment plan. Your child's doctor will determine the correct dose for your baby and the full length of treatment.

Your baby will likely receive the first week of treatment as an inpatient in the hospital. Then, parents or caregivers will generally take over the treatments. Always follow your doctor's instructions about where to give the injection, how much to give, how often, and when to give Acthar Gel to your child. The most common injection schedule is as follows:

  • Weeks 1 and 2: Intramuscular (into a muscle) injections 2 times per day
  • Weeks 3 and 4: Your doctor will provide a schedule to gradually reduce the Acthar Gel dose and number of injections

During treatment, your doctor may check your child's blood pressure regularly. He or she may ask you to make changes to the foods your child eats, such as limiting salt and adding certain supplements.

Injecting Acthar Gel

You may be nervous or worried about giving Acthar Gel injections to your child. Other parents have learned to do it, and you can too. Intramuscular injections of Acthar Gel help ensure that your baby receives the full and correct dose of the treatment.

Talk to your doctor to make sure that you receive injection training resources before your baby is discharged from the hospital or shortly after you arrive home.

Acthar Gel may increase your child’s risk of bleeding from the stomach or developing stomach ulcers. Tell your doctor if your baby has black or bloody stools, bloody vomit, difficulty breathing, or a heart rate that is faster than normal. You should also tell your doctor if your child seems extra tired or extra thirsty, or seems to have stomach pains.

Read the Important Safety Information

Scroll down to read the Important Safety Information. Download the full Medication Guide to see what to expect from Acthar Gel.

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Helpful Resources

Acthar Hub

See the many ways the Acthar Hub can help you get Acthar Gel for your child with IS.

Step-by-step injection guide

Download this informative injection guide to keep handy during your child’s injections.

Download your guide

Treatment calendar

Keep track of your child's injection training schedule and progress.

Download your calendar