About the treatment process


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Acthar Gel is given as an intramuscular (into a muscle) injection. Your child's doctor will determine the correct dose for what is typically a 4-week treatment. Always follow your doctor's instructions about where to give the injection, how much to give, how often, and when to give Acthar to your child. The most common injection schedule is as follows:

  • Weeks 1 and 2: 2 injections per day
  • Weeks 3 and 4: Your doctor will provide a schedule to gradually reduce the Acthar dose and number of injections

Gradually decreasing the amount of Acthar Gel your baby receives in the second half of treatment helps to avoid adrenal insufficiency. Never stop Acthar Gel suddenly. Call your doctor's office if you miss a dose or if you are considering stopping your child's treatment.

When you receive the shipment of Acthar Gel, store it in the refrigerator at 36°F to 46°F (2°C to 8°C). Warm the vial to room temperature before each injection—either by rolling it between your hands or by holding it under your arm for a few minutes.

It's normal to be nervous about giving an injection to your child. Other parents have learned to do it, and you can too. Remember that intramuscular injections of Acthar Gel help ensure that your baby receives the full and correct dose of the treatment. Never inject Acthar Gel under the skin, into a vein, or give it to your child by mouth.

Please review the Important Safety Information below. Also, please review the Medication Guide for all contraindications, warnings, precautions, and adverse events related to Acthar Gel.

Learn how to inject Acthar Gel

Talk to your child's doctor to make sure that you are trained to give your child's Acthar Gel injections. You can also learn about the injection process now.

Helpful Resources

How Acthar Gel may help

Acthar Gel has been proven to stop spasms and hypsarrhythmia in children with IS.

Step-by-step injection guide

Download this informative injection guide to keep handy during your child’s injections.

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Acthar Hub

See the many ways the Acthar Hub can help you get Acthar Gel for your child with IS.