How Acthar Gel may help

A proven treatment for infantile spasms

Acthar Gel (repository corticotropin injection) is a Food and Drug Administration (FDA)-approved medication for infantile spasms (IS) that contains ACTH (adrenocorticotropic hormone), a naturally occurring hormone, which has been proven to stop spasms and hypsarrhythmia in children with IS.

Acthar Gel is a medication that works with your child's body to help it produce its own natural steroids. Your doctor will monitor your child closely during Acthar Gel treatment, so it's important to keep any appointments that are scheduled. You'll need to inject your child with Acthar Gel exactly as your doctor prescribes. Never inject Acthar Gel under the skin, into a vein, or give it to your child by mouth. Never stop Acthar Gel treatment suddenly unless your doctor tells you to.

Acthar Gel has a safety profile that has been well established over many years of use. There are possible side effects you need to be aware of. Acthar Gel has effects on the adrenal gland. When an infant is taking Acthar Gel, his or her adrenal gland may produce too much of a hormone called cortisol. This can cause symptoms of Cushing's syndrome (upper body fat, rounded face, thin skin), which is more common in patients who take this medicine for a long time. When a patient stops taking Acthar Gel after a long time, the body may not produce enough cortisol on its own (adrenal insufficiency). The doctor may prescribe a steroid medicine to protect the body until the adrenal gland recovers. Tell your doctor right away if your child experiences weight loss, feels weak or tired, has stomach pain, or develops a fever. Do not stop administering Acthar Gel without talking to your doctor first.

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Helpful Resources

Acthar Hub

See the many ways the Acthar Hub can help you get Acthar Gel for your child with IS.

Step-by-step injection guide

Download this informative injection guide to keep handy during your child’s injections.

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Treatment calendar

Keep track of your child's injection training schedule and progress.

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