A proven history of IS treatment


Download the Parent and Caregiver Brochure:

Multiple clinical trials have proven that Acthar stops spasms and hypsarrhythmia, the hallmarks of successful treatment for infantile spasms (IS). In fact, in the pivotal clinical study, 87% of children (13 out of 15) had no spasms and no hypsarrhythmia by week 2 of receiving Acthar 75 U/m2 twice a day.

The most common side effects of Acthar in infants include infections, increased blood pressure, irritability and changes in behavior, changes in appetite and weight, diarrhea, and vomiting. Other adverse reactions reported in adults and children over 2 years of age included abdominal bloating, anxiety, asthma, chest discomfort, congestive heart failure, dizziness, shortness of breath, redness of the face, fluid retention, flushing, headache, injection-site pain, tiredness, muscle weakness, nervousness, rapid heart rate, and lack of energy. Tell your doctor if there is any side effect that bothers your child or that does not go away.

Read more about Acthar for IS

For an in-depth look at Acthar treatment for IS, download the Parent and Caregiver Brochure.

Dosing makes a difference

The FDA-recommended dosage of Acthar is 75 U/m2 given to children 2 times each day for the first 2 weeks of treatment, which is based on the results from clinical studies.

While Acthar has been shown to be an effective treatment for IS, it does not treat or cure any underlying disease or injury that may be causing it. Also, it's important to keep in mind that every child responds to treatment differently.

Your doctor will monitor your child during treatment with Acthar. It's very important to keep these appointments. Never stop your child's Acthar treatment suddenly unless your doctor tells you to.

Helpful Resources

Meet Acthar families

Watch others who have been through the entire process of diagnosis and treatment tell you in their own words what to expect when a child has IS.

Learn how to give Acthar

Step-by-step videos help you walk through the administration process so you can learn, and then review, at your own pace.

Treatment calendar

Keep track of your child's injection training schedule and progress.

Download your calendar